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Core Facilities


Advanced Optical Facility - AOF - part of MRSEC

The facility provides instrumentation for the optical and spectroscopic characterization of materials with special emphasis on the non-linear optical response.

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Advanced Photon Source - DuPont, Northwestern, Dow Collaborative Access Team - DND-CAT

DND-CAT supports a broad range of scientific and engineering research programs that need the high X-ray brightness of the Advanced Photon Source. The DND-CAT facility, located at APS Sector-5, has hard X-ray capabilities that include; SAXS, WAXS, XRD, EXAFS, XRR, SXRD, and XSW.

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Advanced Photon Source - Life Sciences Collaborative Access Team - LS-CAT

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Behavioral Phenotyping Core Facility - BPC

The Behavioral Phenotyping Core helps investigators examine their mice and rats for changes in behavior. BPC's mission is to make available to funded research projects a facility to determine the behavioral effects of genetic manipulations, potential pharmaceuticals, aging, and other manipulations upon normal behavior, and the learning and memory capacities of rodents used as model systems. We can also work with PIs needing to gather pilot data.

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Bioethics Consultation and Research Core

Our Center actively researches and engages ethical reflection on the pioneering scholarship being carried out at Northwestern University. It also serves as a physical space for the interdisciplinary dialogue of faculty and students at Northwestern University, a neutral space where researchers and professors from medicine, law, philosophy, religion, chemistry, physics, and engineering can come together and have a conversation that helps the worlds of research, science, and the public understand one another.

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Bioinformatics Core

The Bioinformatics Core Facility provides analysis, support and design for microarrays, proteomics, next generation sequencing, clinical trial informatics as well as custom web-based database development for basic science and clinical projects.

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Biological Imaging Facility - BIF

The Biological Imaging Facility is a shared-use research and training resource available to all NU researchers. BIF is organized so users can prepare samples, capture and analyze images, and create final presentations in one facility. Training for all instruments is available on a regular basis so users can acquire data quickly and efficiently. We are continuously looking for new ways to enhance existing equipment, acquire new tools, and keep pace with current techniques.

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Biologics Production Core

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Biostatistics Collaboration Center

The Biostatistics Collaboration Center provides statistical support and expert consultation for the planning, design, development and execution of studies, and the analysis and interpretation of data, as well as the preparation of reports and manuscripts for basic science, clinical and epidemiologic research projects.

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Cell Imaging Facility - CIF

The Cell Imaging Facility offer state-of-the art instrumentation and services for the study of biological processes at the tissue, cellular and subcellular levels. The facility's services include light, fluorescence, confocal, and electron microscopy, microinjection, digitally controlled temperature stage for live cell observation, computerized image analysis, and digital image manipulation. Specialized imaging techniques include: FRAP, FRET, FLIP, photoactivation, photoconversion, immunogold, etc.

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Center for Advanced Molecular Imaging - CAMI

The Center for Advanced Molecular Imaging provides access to imaging modalities ranging from the nanometer scale to whole animal imaging.

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Center for Atom Probe Tomography - NUCAPT - part of MRSEC

Atom-probe tomography (APT) produces a three-dimensional ( 3D ) atom-by-atom image with sub-nanometer spatial resolution, of a typically 150x150x500 nm^3 volume. APT is particularly suited to study nano or nanostructured materials. NUCAPT operates a CAMECA LEAP4000XSi tomograph. Specimen preparation of almost any material is possible by FIB ( Focused-ion beam milling ). Ion-beam sputtering is used to make surfaces accessible for APT. Tips can also be prepared by ectropolishing.

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Center for Translational Imaging (CTI)

CTI is the Department of Radiology's MRI research facility that is capable of high-end human and animal MR imaging. CTI has the infrastructure and staff to support all types of imaging research studies. See the website for more information.

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Central Laboratory for Materials Mechanical Properties - CLaMMP - part of MRSEC

...The Central Laboratory for Materials Mechanical Properties (CLaMMP) contains testing machines and accessories for conducting educational, research, and outreach experiments on most solid materials. The lab is available for use for both the Northwestern community and non-Northwestern researchers on an hourly-fee basis. The facility provides testing equipment for studying the mechanical behavior of materials.

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ChemCore - Medicinal and Synthetic Chemistry Core, CMIDD

ChemCore provides synthetic chemistry, medicinal chemistry and computational chemistry and molecular modeling services. ChemCore also provides instrumentation for compound purification and characterization.

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Electron Probe Instrumentation Center - EPIC - part of NUANCE

The Electron Probe Instrumentation Center (EPIC- NUANCE) offers a wide range of electron microscopy (both transmission and scanning), accessory instrumentation, and expertise to the scientific and engineering community through education, collaboration, and service. The laboratory provides facilities for the preparation and examination of many types of bulk and thin specimens (foils/films), fine particles, and replicas, including biological materials, by transmission and scanning electron microscopy.

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Flow Cytometry Core Facility - Cancer Center

...The Flow Cytometry Core Facility provides cell sorting services and access to routine flow cytometry assays such as immunophenotyping and DNA analysis as well as guidance, technical assistance and equipment for the investigators to utilize more complex mult-parametric, multi-laser measurement and cell sorting in their research. The recent acquisition of the MoFlo high-speed sorter has increased the facilities technical capabilities.

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Genomics Core Facility

...The genomics core at the Center for Genetic Medicine is a shared resource facility that provides a wide range of services to Cancer Center members and the Northwestern University research community. Our goal is to provide services using the state-of-the-art technologies at an affordable price. We provide expression analysis and SNP analysis using both Affymetrix and Illumina platforms, RT-PCR and low density SNP analysis using 7900HT

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High Throughput Analysis Lab - HTAL

The HTA provides academic, industrial, and private researchers with equipment and expertise for the development and execution of high throughput biological analysis and screening. The facility is fully equipped with state-of-the-art liquid handling, plate detection and automated microbial culture handling capabilities.

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Human Embryonic Stem Cell Facility

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IBNAM Equipment Core

The IBNAM Equipment Core houses state-of-the-art research equipment which allows for the evaluation of samples on cellular and molecular level. The core serves Institute members, NU researchers, and other local academic and commercial labs. Material samples can be lyophilized and biological and chemical samples can be thoroughly analyzed using the core equipment.

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IBNAM Nanomedicine Cleanroom

The IBNAM Nanomedicine Cleanroom Core Facility is specifically designed for interdisciplinary research at the interface of physical and biological sciences. A fully functional photolithography line is located in the class 100 room. This room houses a mask aligner/exposure system, a spin coater, hot plates, and a laminar flow fume hood. The class 10,000 room incorporates a cell culture area, complete with a tissue culture hood, two incubators, a centrifuge, and a cell culture microscope.

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IBNAM Peptide Synthesis Core

The IBNAM Peptide Synthesis Core provides state-of-the-art laboratory equipment, technical services, and support for members of the Institute, other Northwestern University researchers, and the Chicago and regional research community. Technical services include: Custom Peptide Synthesis from 0.1 to 2 mmol scales, HPLC Purificaion, Molecular Weight Determination by MS, LC-MS, and Proteomics Study. We also provide training, data analysis, and technical assistance.

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Instrument Shop - Evanston

...The Northwestern University Instrument shop is a full service machining, fabrication and repair facility capable of meeting the needs of an active research community. We support researchers in the physical and life sciences. The shop is staffed by four highly talented instrument makers with over 150 years experience. The Instrument Shop is a fully equipped machine shop outfitted with manual and CNC (computerized numerical control) machines.

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Integrated Molecular Structure Education and Research Center - IMSERC

Under Construction

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Jerome B. Cohen X-ray Diffraction Facility - part of MRSEC

The primary function is to provide general-purpose x-ray equipment for diffraction studies. The facility can also make accommodations for non-routine experiments such as, special attachments for high and low temperatures, vacuum or protective atmospheres, monochromators, special detectors, etc.

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Keck Biophysics Facility - Keck Bio

The Keck Biophysics Facility provides researchers with 24-hour access to a collection of advanced instruments for biophysical and biochemical characterization of macromolecules and their interactions. Training, technical expertise and assistance are provided by the facility personnel. Staff service on selected instruments is available.

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Keck Interdisciplinary Surface Science Center - Keck II - part of NUANCE

XPS, ToF SIMS, FT-IR, Confocal Raman, IR microscope, Stylus Profilometer, Spectroscopic Ellipsometer

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Mary Beth Donnelley Clinical Pharmacology Core Facility

The Donnelley Clinical Pharmacology Core Facility was established to provide investigators with pharmacokinetic support for preclinical and clinical studies of cancer chemotherapeutic agents, opioids, analgesics, hypnotics, sedatives, and other small molecules. Support includes optimizing the design, conduct, analysis, and interpretation of the pharmacokinetic portion of the study. Plasma drug concentrations can be measured with LC-MS/MS and the plasma drug concentration versus time relationships modeled.

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Materials Processing & Microfabrication - Cleanroom - part of MRSEC

...The Materials Research Center (MRC) cleanroom facility is devoted to materials processing, growth, device fabrication, and electronic & photonic materials. The MRC cleanroom complex in Cook Hall provides microfabrication and thin film processing capabilities. Facility includes class 100 and 1000 cleanrooms. The facility provides microfabrication tools for general use by the Northwestern community, government and industrial researchers.

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Monoclonal Antibody Facility

...The Monoclonal Antibody Facility provides investigators access to the technology for the efficient creation of hybridoma cell lines and the production of monoclonal antibodies from these cell lines. These services include immunization of animals, somatic cell fusion, cloning and screening of hybridomas, subcloning and establishment of antibody producing cell lines, and production of active antibodies from hybridoma cell lines.

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Mouse Histology and Phenotyping Laboratory - MHPL

The purpose of the facility is to assist investigators with their research histology needs, as well as gross and histological characterization of genetically modified murine models. Studies can be performed on individual organs or involve a systemic overview of all major organ systems. Pathologist consultation will allow the development of strategies to elucidate the phenotype and gain mechanistic insight regarding the biologic actions of the targeted molecule.

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Nanoscale Integrated Fabrication, Testing and Instrumentation Center - NIFTI - part of NUANCE

Our three facilities, EPIC, NIFTI, and Keck-II, are committed to- *enhancing education & research by providing a prudent combination of state-of-the-art and core surface science analytical characterization instruments *assisting users by offering hands-on instrument skills training & up-to-date information on concepts, and to collaborate in classroom instruction and research activities *developing innovative research programs and cutting-edge techniques for atomic and nanoscale materials characterization

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NUFAB Cleanroom

NUFAB is an advanced micro/nano fabrication research facility at Northwestern University. It provides resources for research in MEMs/NEMs, nano-bio, nano/microelectronics, and other related and interdisciplinary areas to Northwestern University community and outside researchers. It currently resides in EG20-NG32 Tech Institute and has all new research equipment. Please check the equipment list on this site. In 2012, it will relocate to a new clean room facility at FG infill that is under construction.

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Optical Microscopy & Metallography Facility - OMM - part of MRSEC

This facility is equipped for the metallographic preparation of specimens by producing strain-free surfaces usually examined by optical microscopy. Other applications of mechanically polished specimens involve producing strain-fee (surface) tensile specimens, optically flat electrodes, and flat substrates for subsequent thin-film depositions. Both transmitted light and reflected light metallographs are available for photomicrography and microstructural characterizations.

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Outcomes Measurement & Survey Core - OMSC

The Outcomes Measurement and Survey Core (OMSC) serves the needs of the cancer researchers within the Robert H. Lurie Comprehensive Cancer Center. The mission of this core facility is to provide consultation and support for research that involves collecting, analyzing or interpreting self-report data in culturally diverse populations. The OMSC is housed within the Department of Medical Social Sciences, which also provides similar services to any member of the Northwestern community.

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Pathology Core Facility

...The Pathology Core Facility has three main components: research histology, specimen procurement/banking and protocol review/clinical trial support. The research histology component provides all of the tissue processing and histology services typically performed in a clinical laboratory but it is specifically dedicated to the needs of the Northwestern University research community in general and the Cancer Center research community in particular.

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Quantitative Bioelemental Imaging Center - QBIC

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Rodent Metabolism Phenotyping Core

Our core offers varies analysis of metabolic phenotypes including body composition using NMR.

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Skin Disease Research Center

The goal of the NU-SDRC is to promote first-class translational research in epithelial biology, ultimately to improve patient care. The NU-SDRC is comprised of four distinct cores which include the Administrative Core, the Keratinocyte Core, the Pathology Core and the DNA/RNA Delivery Core. The Core facilities are designed to help NU-SDRC investigators accomplish their research goals related to epithelial cell biology and to provide a level of support to newly recruited junior investigators.

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Structural Biology Facility

The facility is essential for the research programs of investigators who are studying the relationship between macromolecular structure and function or who are using protein structure as the starting point for structure-based drug design. The Structural Biology Facility is a unique resource at Northwestern University that capitalizes on the extensive expertise of a large group of users and regular access to the synchrotron radiation X-ray source at the LS-CAT at the Advanced Photon Source of Argonne Lab.

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Transgenic and Targeted Mutagenesis Laboratory - TTML

The Northwestern University Transgenic and Targeted Mutagenesis Laboratory (TTML) is a shared resource that provides a broad range of services to NU investigators, including generation of transgenic mice, gene targeting of embryonic stem (ES) cells, ES cell microinjection into blastocysts, mouse germplasm cryopreservation, recovery of cryopreserved mouse lines, and rederivation of pathogen free mouse strains.

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